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Shafi, Majid
- Haematological Study on the Fungicide Ziram Induced Acute, Subacute and Subchronic Toxicity in Broiler Chickens
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Authors
Majid Shafi
1,
Shayaib Ahmad Kamil
1,
Masood Saleem Mir
1,
Mohammed Maqbool Darzi
1,
Abdul Shakoor Bhat
1,
Showkat Shah
1,
Khadim Hussain Dar
1
Affiliations
1 Division of Veterinary Pathology, Shuhama, Alusteng, Sher‑e‑Kashmir University of Agricultural Sciences, Kashmir, IN
1 Division of Veterinary Pathology, Shuhama, Alusteng, Sher‑e‑Kashmir University of Agricultural Sciences, Kashmir, IN
Source
Nature Environment and Pollution Technology, Vol 15, No 2 (2016), Pagination: 635-639Abstract
The present work was conducted to elucidate the haematological changes in broiler chickens after Ziram intoxication. For this study, 150 apparently healthy broiler chicks were reared up to 2 weeks of age and randomly allocated to four groups, i.e. acute (N=10), sub-acute (N=20), sub-chronic (N=90) and control (N=30). Toxicity was induced following a single oral dose of Ziram @ 100mg/kg body weight for acute intoxication; 5 mg/kg body weight per day for 20 days in case of sub-acute group and 1mg/kg body weight per day for the study period of 90 days in case of sub-chronic intoxication. At the end of the experimental period the investigations revealed significant decrease in haemoglobin concentration, packed cell volume, total erythrocyte count and leucocytosis with heterophilia leading to clinical anaemia.Keywords
Broiler Chickens, Ziram Fungicide, Toxicity, Haematology.Full Text
References
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- Chesterman, H., Heywood, R., Ball, S., Street, A. and Prentice, D. 1998. Metiram oral toxicity study in beagle dogs for period of 4 weeks. Submitted to World Health Organisation by BASF Corporation Limited.
- Dickhaus, S. and Heisler, E. 1980. Report of subacute toxicity study on ziram for four weeks in the Rat. Report No. 2-4-132-80 from Pharmatox, Germany.
- Edwards, I.R., Ferry, D. and Temple, A. 1991. Fungicides and Related Compounds. In: Hayes WJ, Laws ER, editors. Handbook of Pesticide Toxicology. New York: Academic Press, Inc.
- Kanchi, S. 2013. Dithiocarbamates as hazardous remediation agent. Arabian Journal of Chemistry, 7(1): 11-25.
- Michael, K. 1997. Toxicity of pesticides and its impact on environment. Environmental Sciences and Agriculture, pp. 143-147.
- Rasul, A.R. and Howell, J.M. 1974. The toxicity of some dithiocarbamate compounds in young and adult domestic fowl. Toxicology & Applied Pharmacology, 31(1): 63-78.
- Van Leeuwen, C.J., Van Hameren, P., Bogers, M. and Griffionen, P.S. 1986. Uptake, distribution and retention of zineb and ziram in rainbow trout (Salmo gairdneri). Toxicology, 42(1): 33-46.
- Yousef, M. and Al-Salhen, K. 2003. Changes in some hematological and biochemical indices of rabbits induced by isoflavones and cypermethrin. Toxicology, 189(3): 223-234.
- Haemato-Biochemical Studies on Diclofenac, Ibuprofen and Nimesulide Induced Toxicity in Broilers
Abstract Views :211 |
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Authors
Majid Shafi
1,
Umesh Kumar Garg
1,
Najmus Saqib
1,
Omer Khalil Baba
1,
Badru-Duja Farid
1,
Arshad Wali
1
Affiliations
1 Division of Veterinary Pathology, Mhow, Indore, M. P., IN
1 Division of Veterinary Pathology, Mhow, Indore, M. P., IN
Source
Nature Environment and Pollution Technology, Vol 11, No 4 (2012), Pagination: 649-652Abstract
The present experimental work was conducted to elucidate the haemato-biochemical studies in broiler chicks when treated with diclofenac sodium, ibuprofen and nimesulide. For this study 120 apparently healthy broiler chicks of either sex were randomly divided into 10 groups comprising 10 birds in 9 groups and 30 birds in control group. The broilers of diclofenac groups were administered 10, 20 and 30 mg/kg body weight of diclofenac sodium for 5 days. Similarly the broilers of ibuprofen groups were administered with 15, 30 and 45 mg/kg body weight of ibuprofen with feed for 5 days. The birds of nimesulide groups were administered with 10, 20 and 30 mg/kg nimesulide for 5 days. The birds of control group were maintained on feed and plain water to serve as control. There was no significant difference in haematological parameters in birds which are intoxicated with diclofenac, ibuprofen and nimesulide. On the other hand there was significant difference in alkaline phosphatase and BUN biochemical parameters, but no significant difference in total protein and calcium intoxication in chicks.Keywords
Haemato-Biochemical, Studies, NSAIDS, Toxicity, Broilers.Full Text
- Gross and Histopathological Study of Ziram Induced Subchronic Toxicity in Broiler Chickens
Abstract Views :133 |
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Authors
Majid Shafi
1,
Shayaib Ahmad Kamil
1,
Masood Saleem Mir
1,
Mohammed Maqbool Darzi
1,
Abdul Shakoor Bhat
1,
Showkat Ahmad Shah
1,
Omer Khalil Baba
1
Affiliations
1 Division of Veterinary Pathology, Shuhama, Alusteng, SKUAST- Kashmir, IN
1 Division of Veterinary Pathology, Shuhama, Alusteng, SKUAST- Kashmir, IN
Source
Nature Environment and Pollution Technology, Vol 16, No 3 (2017), Pagination: 821-828Abstract
The present experimental work was conducted to elucidate the pathological changes in broiler chickens after ziram intoxication. For this study 120 apparently healthy broiler chicks were reared up to 2 weeks of age and allocated randomly to two groups, i.e. sub-chronic toxicity (N=90) and control group (N=30). Toxicity was induced in broiler chicks by giving 1 mg/kg body weight per day for the study period of 90 days in case of sub-chronic intoxication. At the end of the experimental period the investigations revealed depletion of lymphoid tissue from the lymphoid organs which were suggestive of immunosuppressive and immunomodulatory effects of ziram in chicken.Keywords
Broiler Chickens, Ziram Fungicide, Lymphoid Tissue.Full Text